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Large clinical trials have not confirmed an increased incidence of medullary thyroid carcinoma in humans using GLP-1 medications, though these trials were not designed specifically to assess this rare outcome

The glucagon receptor activation that some researchers worried might raise cardiovascular risk has not produced adverse effects in human trials

LINK Sarcopenia nellobesit e nel diabete Molti studi hanno dimostrato che semaglutide favorisce una significativa riduzione del peso, attribuita prevalentemente alla massa grassa, anche viscerale

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